Medication policy updates

See the table below for a summary of medication policy additions and changes that require provider notification, including pre-authorization requirements. Note: Policies are available online on the effective date of the addition or change.

Pre-authorization: Submit medication pre-authorization requests through CoverMyMeds.

Expert feedback: We routinely assess our medication policies based on updated medical literature, national treatment guidelines, practicing provider feedback and pharmaceutical market changes. If you’d like to provide feedback or be added to our distribution list, please email our Medication Policy team and indicate your specialty.

New FDA-approved medications: New-to-market medications are subject to pre-authorization based on their FDA-labeled indication, pivot trial criteria and dosage limitations until we complete a full medication review and develop a coverage policy.

Product not available (PNA) status: We allow a 90-day grace period to use any existing supply for medications that CMS has designated as PNA before they become ineligible for reimbursement. See our Non-Reimbursable Services (Administrative #107) reimbursement policy.

Last updated: April 1, 2025

Policy name

Policy number

Description

New or revised

Effective date

Notification date

Camzyos, mavacamten

Dru720

The concomitant use of Camzyos with disopyramide is considered investigational and therefore not covered

Revised

July 1, 2025

April 1, 2025

CGRP Monoclonal Antibodies

Dru540

The concomitant use of multiple CGRP agents (oral or injectable) is considered investigational and therefore not covered

Revised

July 1, 2025

April 1, 2025

Hemlibra, emicizumab-kxwh

Dru539

The concomitant use of Hemlibra with other non-factor hemophilia prophylactic products is considered investigational and therefore not covered

Revised

July 1, 2025

April 1, 2025

Medications for transthyretin-mediated amyloidosis

Dru733

  • Updated diagnosis requirement to be by a specialist
  • Updated the NYHA FC I-III requirement to include symptomatic

Revised

July 1, 2025

April 1, 2025

Provider-Administered Specialty Drugs

Dru764

Added the following products to the Provider-Administered Specialty Drug List:

  • J9292 pemetrexed (avyxa)
  • J9294 pemetrexed (hospira)
  • J9296 pemetrexed (accord)
  • J9297 pemetrexed (sandoz)
  • J9322 pemetrexed (bluepoint)
  • J9323 pemetrexed ditromethamin
  • J9324 pemrydi rtu
  • J9044 bortezomib, nos
  • J9051 bortezomib (maia)

Revised

July 1, 2025

April 1, 2025

Self-administered CGRP antagonists and 5-HT 1f agonists

Dru635

The concomitant use of prophylactic agents (oral or injectable) is considered investigational and therefore not covered

Revised

July 1, 2025

April 1, 2025

Site of Care Review

Dru408

Added the following products to the Infusion Drug Site of Care Program; when administered by a provider, these medications will be required to be given at an approved Site of Care location:

  • J1552 immune globulin (alyglo)
  • J2323 natalizumab (tysabri)
  • Q5134 natalizumab-hyphensztn (tyruko), biosimilar

Revised

July 1, 2025

April 1, 2025

Drugs for chronic inflammatory diseases

Dru444

The preferred adalimumab (Humira) products will be certain biosimilars only.

Revised

January 1, 2026

April 1, 2025